Sodium Citrate
Usually made by adding sodium carbonate to a solution of citric acid until effervescence
ceases, evaporating and granulating the product, there is no conclusive evidence disproving
or proving its safety in humans.  Sodium citrate is used to prevent blood coagulation during
blood collection. The liver under normal circumstances can rapidly metabolize sodium citrate;
however an unhealthy liver may have difficulty with this substance potentially resulting in an
accumulation of bicarbonate (the metabolic derivative of citrate) which can cause metabolic
alkalosis.


Hazardous Substances Databank Number: 5201.